Author: Dr. Marc Greenberg, MDLast Reviewed: December 26, 2025
Fellowship-Trained Spine Surgeon

About Dr. Marc Greenberg

Fellowship-trained spine surgeon specializing in minimally invasive and motion-preserving care. Mayo Clinic highest honors; Johns Hopkins residency; Brown University spine fellowship.

Fellowship
Mayo Clinic
Fellowship
Johns Hopkins
Fellowship
Brown University
Dr. Marc Greenberg professional portrait in suit

Professional in Every Setting

Expertise across all aspects of spine care

Dr. Greenberg in the Operating Room

In the Operating Room

Performing advanced minimally invasive procedures

Dr. Greenberg in Professional Setting

Consultations & Leadership

Educating patients and advancing the field

Dr. Greenberg with Patient

Clinic & Patient Care

Personalized treatment planning and follow-up

Meet Dr. Marc Greenberg

Dr. Marc Greenberg is a fellowship-trained orthopedic spine surgeon focused on minimally invasive, robotic, endoscopic, and motion-preserving care. His training pathway runs through three of the nation's premier institutions—Mayo Clinic (MD), Johns Hopkins (Orthopedic Surgery Residency), and Brown University (Spine Fellowship)—a pedigree that underpins his precision-first, recovery-focused approach.

Surgical Precision, Minimally Invasive When Appropriate

Dr. Greenberg's promise is simple: the least invasive option that truly solves the problem. When surgery is appropriate, he prioritizes motion-preserving solutions (e.g., cervical disc replacement) and muscle-sparing techniques (robotic navigation, endoscopic decompression) to reduce pain, shorten hospital stays, and speed a confident return to work, family, and sport.

Dr. Marc Greenberg in the operating room

Philosophy

Dr. Greenberg's promise is simple: the least invasive option that truly solves the problem. When surgery is appropriate, he prioritizes motion-preserving solutions (e.g., cervical disc replacement) and muscle-sparing techniques (robotic navigation, endoscopic decompression) to reduce pain, shorten hospital stays, and speed a confident return to work, family, and sport.

Dr. Marc Greenberg in clinic (white coat)

Clear Diagnosis, Patient-First Planning

Every treatment decision starts with thorough review of MRI or CT imaging to identify the structural cause of symptoms. Dr. Greenberg believes in conservative care first when appropriate, with surgery reserved for cases where non-surgical treatment has not provided adequate relief or when progressive neurological symptoms are present.

Patients receive clear explanations of all appropriate options, realistic expectations about outcomes and recovery, and support in making the decision that aligns with their goals and values.

Clinical Philosophy

  • Imaging-based diagnosis: Every treatment decision starts with thorough review of MRI or CT imaging to identify the structural cause of symptoms.
  • Conservative-first when appropriate: Most spine conditions improve with non-surgical care. Surgery is reserved for cases where conservative treatment has not provided adequate relief or when progressive neurological symptoms are present.
  • Minimally invasive when appropriate; fusion when necessary: Motion-preserving and minimally invasive techniques are prioritized when imaging and symptoms support their use. However, conditions involving instability or deformity may require fusion for optimal outcomes.
  • Shared decision-making: Patients receive clear explanations of all appropriate options, realistic expectations about outcomes and recovery, and support in making the decision that aligns with their goals and values.

Areas Served

Dr. Greenberg is establishing his practice in Fort Wayne, Indiana, serving patients throughout northeast Indiana and northwest Ohio. Patients commonly travel from surrounding communities including Warsaw, Auburn, Huntington, Columbia City, Angola, Kendallville, and Bryan, OH for fellowship-trained spine surgery expertise.

View all areas we serve

Clinical Interests

Cervical disc replacement (ADR), endoscopic cervical/lumbar decompression, MIS TLIF/PLIF, ACDF/cervical foraminotomy, adult deformity, revision surgery, kyphoplasty, and SI joint fusion.

Recognition & Leadership

At Johns Hopkins, Dr. Greenberg served as Chief Resident Director and Chief of Education and was recognized as Emergency Department Consult Resident of the Year (2022–2023) and House Staff Resident of the Month.

Research & Teaching

Dr. Greenberg has contributed peer-reviewed work and book chapters spanning spine outcomes, cost-utility in ACDF, perioperative optimization, and MRI fundamentals, with presentations at national meetings including AAOS and AOFAS. Publications include Spine, JBJS, Journal of Arthroplasty, Seminars in Spine Surgery, and textbook chapters.

Outside the OR

Marc is married to his wife Maayan; they share life with a Golden Retriever puppy. He grew up around horses, still loves to ride, and brings that same calm, steady focus to caring for patients.

As Seen In

Dr. Greenberg's research published in leading medical journals

Journal names are property of their respective owners; links provided for reference only.

Training Timeline

Mayo Clinic
Johns Hopkins
Brown University

Mayo Clinic

Medical School

Alix School of Medicine - Graduated with highest honors, establishing foundation in evidence-based medicine and clinical excellence

Johns Hopkins

Residency

Orthopedic Surgery Residency - Mastered traditional and cutting-edge surgical techniques in one of the nation's most competitive programs

Brown University

Fellowship

Minimally Invasive & Motion-Preserving Spine Surgery Fellowship - Specialized training in the most advanced surgical techniques

Training at these institutions; no endorsement implied.

Selected Honors & Recognition

Academic excellence and clinical leadership throughout medical training and practice

Academic Excellence

  • Magna Cum Laude - Mayo Clinic Alix School of Medicine
  • B.S. with Distinction and Honors - Undergraduate studies
  • Golden Humanism Award - Excellence in compassionate patient care

Clinical Leadership

  • Chief Resident Director - Johns Hopkins
  • Chief of Education - Residency program
  • ED Consult Resident of the Year (2022–2023)
  • House Staff Resident of the Month

Research & Publications

Published in Top Journals

  • • Spine
  • • Journal of Bone & Joint Surgery (JBJS)
  • • Journal of Arthroplasty
  • • Seminars in Spine Surgery

Research Focus

  • • Endoscopic spine surgery techniques
  • • Motion preservation technologies
  • • Cervical disc replacement outcomes
  • • Minimally invasive surgical approaches

"Contributing to the advancement of spine surgery through evidence-based research and clinical studies presented at national meetings including AAOS and AOFAS."

Presentations & Abstracts

M. Greenberg, MD; AA. Aiyer, MD; ICL: Innovative Hindfoot Techniques; AAOS 2023

AAOS

A. Gupta, BS; P. Singh, MS; D. Badin MD, K. Mo, MHA; Marc Greenberg, MD; F. Musharbash, MD; A. Aiyer, MD; Abstract AOA 2023: Racial Disparities in Lower Extremity Orthopaedic Injuries Presenting to U.S. Emergency Departments from 2010–2020

AOA 2023

Frederick Mun; Arjun Gupta; Rachel Bronheim; Marc Greenberg; Micheal Raad; Ettore Vulcano; Anish R. Kadakia; Amiethab Aiyer; The Effects of Electronic Nicotine Delivery Systems on Musculoskeletal Health: A Systematic Review; Abstract EOA 2022

EOA 2022

Benes G, Ghanem D, Badin D, Greenberg M, Honcharuk E. L'effet de la privation socio-économique sur les déformations radiographiques chez les enfants atteints de la maladie de Blount. Presented at 97th Société Française de Chirurgie Orthopédique et Traumatologique Congress; November 13-15, 2023; Paris, France. [Oral Presentation]

International

Gupta, A., Singh, P., Badin, D., Mo, K.C., Greenberg, M., Musharbash, F.N., Hughes, A.J., Ficke, J.R., and Aiyer, A.A. Black/African Americans Experience Disparate Outcomes after Lower Extremity Orthopaedic Injury Evaluation in U.S. Emergency Departments. 2023 American Orthopaedic Foot and Ankle Society (AOFAS) Annual Meeting, Louisville, KY. September 2023

AOFAS 2023

Mo, K., Gupta, A., Movsik, J., Covarrubias, O., Greenberg, M., Riley, L., Kebaish, K., Neuman, B., and Skolasky, R.L. Self-Efficacy and Daily Preoperative Opioid Use in Elective Spine Surgery Patients. 2023 Rutgers NJMS Annual Research Symposium, Newark, NJ. April 2023

Research Symposium

Benes G, Ghanem D, Badin D, Greenberg M, Honcharuk E. The Effect of Socioeconomic Deprivation on Radiographic Deformities in Children with Blount Disease. Presented at 2nd annual Medical Student Orthopedic Symposium (MSOS); April 23, 2023. [e-poster presentation]

MSOS 2023

Raad M, Xu A, Ortiz-Babalonia C, Durand W, Greenberg M, Jain A. A 5-Year Cost-Utility Analysis Comparing Synthetic Cage vs Allograft Use in Anterior Cervical Discectomy and Fusion Surgery for Cervical Spondylotic Myelopathy. Global Spine Congress; June 2023; Prague, Czech Republic

Global Spine Congress

Mo, K., Gupta, A., Movsik, J., Covarrubias, O., Greenberg, M., Riley, L., Kebaish, K., Neuman, B., and Skolasky, R. Pain Self-Efficacy (PSEQ) Score of <22 is Associated with Daily Opioid Use, Back Pain, Disability, and PROMIS Scores in Patients Presenting for Spine Surgery

Spine Research

Benes G, Badin D, Greenberg M, Honcharuk E. Can Socioeconomic Factors Explain Racial Differences in Disease Severity and Treatment in Blount Disease? Presented at International Pediatric Orthopaedic Symposium; December 6-10, 2022; Orlando, FL. [Poster Presentation]

IPOS 2022

Mark Haft, BS; Amil R. Agarwal, MD; Hannon Levy, MD; Theodore Quan, MD; Marc Greenberg, MD; Michael Raad, MD; Tushar Patel, MD; Amit Jain, MD; AAOS 2023: Data-Driven Preoperative Hemoglobin Strata that Maximize the Likelihood of Blood Transfusion following Single-Level Lumbar Fusion Are Also Predictive of Major Complications and Deep Infections

AAOS 2023

Amy L. Xu, BS, Christopher J. Murdock, MD, Jalen Warren, BS, Shivani Pandya, BS; Marc Greenberg, MD; Rachel Sotsky, MD; and Amiethab A. Aiyer, MD; Operative versus Nonoperative Management of Calcaneal Fractures: A Cost Analysis; MOA 2023. Abstract Presentation

MOA 2023

Juan S. Vargas-Hernandez, M.D.; Marc Greenberg, M.D.; Brandon J. Yuan, M.D. Cannulated Screws or Hemiarthroplasty for Femoral Neck Fractures: Is There a Difference in Mortality? MOA 2020

MOA 2020

Marc Greenberg, M.D.; Juan S. Vargas-Hernandez, M.D.; Brandon J. Yuan, M.D. Operative Treatment Delays of Vancouver B2 Fractures are Not Associated with Increased Mortality. Abstract MOA 2020

MOA 2020

Vargas-Hernandez, MD; Marc Greenberg B.S; Jonathan Barlow, MD; William W. Cross III, MD; Andrew Sems, MD; Brandon J. Yuan, MD; Are the Outcomes of Internal Fixation for Intertrochanteric Fractures Affected by Overlapping Surgery? A Retrospective Study Abstract MOA 2020

MOA 2020

Juan S. Vargas-Hernandez, M.D.; Marc Greenberg, M.D.; Brandon J. Yuan, M.D. Cannulated Screws or Hemiarthroplasty for Femoral Neck Fractures: Is There a Difference in Mortality? OTA 2023

OTA 2023

Additional Publications

Victor B. Yang; Henry Shu; Manuj M. Shah; Xiyu Zhao; Siam T. Muquit; Marc Greenberg; Glenn Whitman; Sung-Min Cho; Bo Soo Kim; Babar Shafiq; Cureus Journal: Atraumatic Polycompartment Syndrome Secondary to Cardiogenic Shock: A Case Report

Cureus Journal

Why Greenberg Spine

Smaller incisions. Less pain. Faster, safer recovery—grounded in Mayo • Johns Hopkins • Brown training.

Elite Training

Mayo Clinic, Johns Hopkins, and Brown University fellowship training in the most advanced techniques

Advanced Technology

Robotic navigation, endoscopic techniques, and state-of-the-art surgical equipment

Motion Preservation

Prioritizing techniques that maintain natural spine movement whenever possible

Selected Publications

Contributing to the advancement of spine surgery through research and clinical studies

The Cervical Spine

OKU Sports Medicine 6, Chapter 32, 2023

Cervical SpineSports MedicineTextbook Chapter

Essentials of MRI Physics and Pulse Sequences

MRI for Spine Physicians 3rd edition: Chapter 1, 2023

MRIImagingSpineTextbook Chapter

Preoperative Evaluation and Surgical Counseling in the Elderly

Seminars in Spine Surgery, 2020

Elderly CarePreoperative EvaluationSurgical Planning

Is primary total elbow arthroplasty appropriately compensated compared to other major total joint arthroplasty?

Seminars in Arthroplasty: JSES, 2023

ArthroplastyHealthcare EconomicsElbow Surgery

Free Falling: Declining Inflation-Adjusted Payment for Arthroplasty Surgeons

The Journal of Arthroplasty, 2023

Healthcare EconomicsArthroplastyPayment Analysis

The Effect of Socioeconomic Deprivation on Radiographic Deformities in Children with Blount Disease

JBJS, 2024

Pediatric OrthopedicsBlount DiseaseSocioeconomic Factors

The Effects of Electronic Nicotine Delivery Systems on Musculoskeletal Health: A Systematic Review

Archives of Orthopaedic and Trauma Surgery, 2022

Systematic ReviewNicotineMusculoskeletal Health

Operative Treatment Delays of Vancouver B2 Fractures are Not Associated with Increased Mortality, Revision, or Reoperation

Journal of Arthroplasty, 2023

Fracture ManagementVancouver ClassificationArthroplasty

Cost-Utility Analysis Comparing Laminectomy with Fusion versus Laminoplasty

5 Year Residency Research Project, In Progress

Cost AnalysisLaminectomyLaminoplastyCervical Spine

Third-party links — no endorsement implied.

Why Greenberg Spine

Advanced training, cutting-edge technology, and motion-preserving philosophy

Elite Training

Mayo Clinic, Johns Hopkins, and Brown University fellowship training in the most advanced techniques

Advanced Technology

Robotic navigation, endoscopic techniques, and state-of-the-art surgical equipment

Motion Preservation

Prioritizing techniques that maintain natural spine movement whenever possible

Experience Expert Spine Care

Discover how Dr. Greenberg's expertise and minimally invasive approach can help you return to the activities you love.